| | | | HEURE | STADE | HOTE | SCORE | VISITEUR | RETRANSMIS PAR | | | | Jeudi 16 Février 2023 | | | | 18:45 |  |  | Qarabag FK |
| 1 - 0 | | La Gantoise |  |
|  | | 18:45 |  |  | Trabzonspor |
| 1 - 0 | | FC Bâle |  |
| | | 18:45 |  |  | FK Bodo Glimt |
| 0 - 0 | | Lech Poznan |  |
| | | 18:45 |  |  | Sporting Braga |
| 0 - 4 | | Fiorentina |  |
| | | 21:00 |  |  | Lazio Rome |
| 1 - 0 | | CFR Cluj |  |
| | | 21:00 |  |  | AEK Larnaca |
| 1 - 0 | | SK Dnipro-1 |  |
| | | 21:00 |  |  | Sheriff Tiraspol |
| 0 - 1 | | Partizan Belgrade |  |
| | | 21:00 |  |  | Ludogorets Razgrad |
| 1 - 0 | | Anderlecht |  |
| | | | | Jeudi 23 Février 2023 | | | | 18:45 |  | | CFR Cluj |
| 0 - 0 | | Lazio Rome | |
| | | 18:45 |  | | SK Dnipro-1 |
| 0 - 0 | | AEK Larnaca | |
| | | 18:45 |  | | Partizan Belgrade |
| 1 - 3 | | Sheriff Tiraspol | |
| | | 18:45 |  | | Anderlecht |
| 2 - 1 ap. (3 tab 0) | | Ludogorets Razgrad | |
| | | 21:00 |  | | La Gantoise |
| 1 - 0 ap. (5 tab 3) | | Qarabag FK | |
| | | 21:00 |  | | FC Bâle |
| 2 - 0 | | Trabzonspor | |
| | | 21:00 |  | | Lech Poznan |
| 1 - 0 | | FK Bodo Glimt | |
| | | 21:00 |  | | Fiorentina |
| 3 - 2 | | Sporting Braga | |
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